New PDF release: Varicella-Zoster Virus: Virology and Clinical Management

By Ann M. Arvin, Anne A. Gershon

ISBN-10: 0521660246

ISBN-13: 9780521660242

The winning improvement of a VZV vaccine displays excessive learn curiosity during this virus over contemporary years. This accomplished account of the biology and medical good points of the varicella-zoster virus, released in organization with the VZV learn beginning, surveys present wisdom of the molecular biology, pathogenesis, and medical positive aspects of VZV because the causative agent of chickenpox and zoster (shingles). the amount covers such subject matters as viral replication, latency, immune mechanisms, epidemiology and disorder manifestations, and problems of varicella and zoster. additionally integrated is special details on dwell attenuated varicella vaccine, remedy suggestions, and the administration of postherpetic ache in zoster sufferers. because the so much authoritative assessment and consultant to the virus and its ailments, this booklet will attract quite a lot of clinicians and investigators, together with pediatricians, geriatricians, neurologists, dermatologists, infectious ailment experts, and virologists drawn to the herpes viruses.

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Additional info for Varicella-Zoster Virus: Virology and Clinical Management

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Despite the differences resulting from long periods of separate evolution, ␣-, ␤and ␥-herpesviruses share a substantial genetic heritage and thus may be presumed to have evolved from an ancestor that would have been clearly recognizable as a herpesvirus. , 1999). The two groups of viruses recognizably share only a single gene (UL15 in HSV-1) that lacks a cellular counterpart and therefore may have been derived from a common ancestor. , 1983; Davison, 1992; Davison & Davison, 1995). Given this state of apparent genetic isolation, these two major groups of herpesviruses (mammalian, avian and reptilian herpesviruses on the one hand, and fish and amphibian herpesviruses on the other) sit together rather uncomfortably.

Fagge, C. H. (1886). In Principles and Practice of Medicine, volume I, pp. 250–4. Philadelphia: P. Blakiston, Son and Co. Feldman, S. (1994). Varicella-zoster virus pneumonia. Chest, 106, (Suppl. S22–S27). Garland, J. (1943). Varicella following exposure to herpes zoster. N. Engl. J. , 228, 336–7. Gershon, A. A. (1995). Development of live attenuated varicella vaccine. Proc. Assoc. Am. Physicians, 107, 365–8. Gershon, A. , Gelb, L. & NIAID-Collaborative-Varicella-Vaccine-Study-Group (1984). Live attenuated varicella vaccine: efficacy for children with leukemia in remission.

Balfour Jr, H. H. (1989). Varicella and herpes zoster. In Infectious Diseases, ed. P. D. Hoeprich & M. C. Jordan, pp. 942–53. Philadelphia: Lippincott. Fagge, C. H. (1886). In Principles and Practice of Medicine, volume I, pp. 250–4. Philadelphia: P. Blakiston, Son and Co. Feldman, S. (1994). Varicella-zoster virus pneumonia. Chest, 106, (Suppl. S22–S27). Garland, J. (1943). Varicella following exposure to herpes zoster. N. Engl. J. , 228, 336–7. Gershon, A. A. (1995). Development of live attenuated varicella vaccine.

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Varicella-Zoster Virus: Virology and Clinical Management by Ann M. Arvin, Anne A. Gershon


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