By Simon Shorvon
This booklet offers an intensive reappraisal of prestige Epilepticus, the severest expression of epilepsy. within the gentle of contemporary study it conscientiously examines present therapy, significantly difficult latest tenets. A scheme of type is proposed established no longer exclusively on seizure style but in addition on age, pathophysiological mechanisms and medical positive factors, contemplating the place attainable the scientific points of prestige within the context in their clinical foundation, no matter if this can be epidemiology, neurophysiology, neuropathology or neuropharmacology. a pragmatic bias is maintained all through, according to scientific adventure, with maximum house dedicated to therapy, together with reports of efficacy and toxicity of person medicinal drugs and necessary use of tables to obviously summarize key details. this can be a uniquely accomplished evaluate of the big quantity of released literature during this box and should act as a useful reference paintings and useful advisor for quite a lot of training clinicians, from neurologists, psychiatrists and paediatricians during to these concerned basically in emergency drugs.
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Additional info for Status Epilepticus: Its Clinical Features and Treatment in Children and Adults
Of status can be calculated to be 100-200 per 1 000 000 persons in the general population. 9. Other status syndromes: West syndrome, the neonatal and childhood status syndromes, epilepsia partialis continua, simple partial status, and absence status in the elderly are rare, and can contribute to the annual incidence of status no more than 5-10 cases per 1 000 000 persons in the general population (at a conservative and approximate estimate). The boundary syndromes have not been included in these calculations, but are relatively common.
13% of all casualty visits; Pilke, Partinen & Kovanen 1984). Status epilepticus as a proportion of all epileptic cases Turner's (1907) estimate that a history of status had occurred in about 5% of his clinic cases was roughly confirmed by subsequent studies, at least until recent times. 3% (27 of 1166) of patients of whom about half were over 40 years. In children the incidence is higher. Aicardi & Chevrie (1970) found status in 16% of children with the diagnosis of epilepsy before the age of 16 years.
Subdivision on purely EEG grounds is avoided. Frequency of status epilepticus If one cannot easily define a condition or indeed satisfactorily classify it, clearly any estimate of its frequency must be of doubtful validity; this is the position with status. Until very recently, all computations of frequency were restricted to tonic clonic status, but even here only the vaguest guesses at incidence or prevalence were possible. Hunter (1959/60) contrasted the increasingly frequent references to status in the second half of the nineteenth century with the paucity of earlier reports, and inferred that the condition became common only with the appearance of effective antiepileptic drugs (bromides).
Status Epilepticus: Its Clinical Features and Treatment in Children and Adults by Simon Shorvon