Download PDF by Edgar Pick: Lymphokines. A Forum for Immunoregulatory Cell Products

By Edgar Pick

ISBN-10: 0124320147

ISBN-13: 9780124320147

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1984). Infect. Immun. 45, 483-491. 30 CHARLES A. DINARELLO Hanson, D. , Murphy, P. , and Shin, H. S. /. Immunol. 130, 216-221. , and Dinarello, C. A. (1985). / . Leuk. Biol. 37, 713. Jampel, H. , Duff, G. , Gershon, R. , and Durum, S. K. (1983). /. Exp. Med. 157, 1229-1238. Kampschmidt, R. F. (1981). In "The Physiologic and Metabolic Responses of the Host" (M. C. Powanda and P. G. ), pp. 55-74. Elsevier/North Holland, Amsterdam. Kampschmidt, R. , and Pulliam, L. A. (1978). Proc. Soc. Exp. Biol.

Clin. Oncol. 4, 1380-1391. Auron, P. , Webb, A. , Rosenwasser, L. , Mucci, S. , Wolff, S. , and Dinarello, C. A. (1984). Froc. Natl. Acad. Sei. A. 8 1 , 7907-7911. Auron, P. , Rosenwasser, L. , Dinarello, C. , Oppenheim, J. , and Webb, A. C. (1985). / . Mol. Immunol. 2, 169-177. Bachwich, P. , Chensue, S. , Larrick, J. , and Kunkel, S. L. (1986). Biochim. Biophys. Res. Commun. 136, 94-101. Beeson, P. (1948). / . Clin. Invest. 27, 524. Bernheim, H. , and Dinarello, C. A. (1985). YaleJ. Biol. Med.

Ated cytoplasmic, immunoprecipitable proteins which appear similar to those revealed by translation of the monocyte mRNA. Figure 5 demonstrates that these proteins are found primarily within the cell cytoplasm and are only seen extracellularly following concentration (lane L). The intracellular 31,000 MW protein is stabilized in the presence of the serine protease inhibitor phenylmethylsulfonyl fluoride (PMSF) (lanes A-C), thus supporting the conclusion that the lower molecular weight forms of IL-1 are probably derived from a larger precursor.

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Lymphokines. A Forum for Immunoregulatory Cell Products by Edgar Pick


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