By William R. Proffit DDS PhD, Henry W. Fields Jr. DDS MS MSD, David M. Sarver DMD MS
Modern Orthodontics, fifth variation, is a pragmatic source with a protracted culture of excellence. This variation has been widely revised to keep up the unique target of the ebook: to supply an up to date evaluation of orthodontics that's available to either undergraduate and postgraduate scholars and a precious reference for practitioners...The key parts primary in buying modern orthodontic abilities are summarised in a coherent style. this article merits to develop into the vade mecum for the aspiring orthodontist or clinician.
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C. Platelet-Activating Antibodies in the Pathogenesis of HIT Although some limited studies of heparin-dependent platelet aggregation by patient serum were performed in the classic study by Rhodes and colleagues (1973), the next few years saw increasing emphasis on this characteristic feature of HIT antibodies. In 1975, National Institutes of Health investigators Fratantoni et al. described a patient who developed severe thrombocytopenia (4 · 109/L) and pulmonary embolism while receiving therapeutic-dose unfractionated heparin (UFH) to treat deep venous thrombosis.
J Clin Ther Med 2:1645, 1986. Tardy B, Tardy-Poncet B, Fournel P, Venet C, Jospe R, Dacosta A. Lower limb veins should be systematically explored in patients with isolated heparin-induced thrombocytopenia [letter]. Thromb Haemost 82:1199–1200, 1999. Towne JB, Bernhard VM, Hussey C, Garancis JC. White clot syndrome. Peripheral vascular complications of heparin therapy. Arch Surg 114:372–377, 1979. Trowbridge AA, Caraveo J, Green JB III, Amaral B, Stone MJ. Heparin-related immune thrombocytopenia.
The plateletactivating factor was presumed, but not proved, to be caused by an antibody. , 1980). , patient globulin fractions incubated with heparin, platelet-rich plasma, and celiteactivated contact product shortened the clotting time following recalcification). Three patients developed thrombotic complications, and none developed hemorrhage. ” 6 Warkentin A consistent theme was evident from these various reports. Patients developed arterial or venous thrombotic complications, in association with thrombocytopenia that generally began after 5 or more days of heparin treatment.
Contemporary Orthodontics by William R. Proffit DDS PhD, Henry W. Fields Jr. DDS MS MSD, David M. Sarver DMD MS