Download PDF by George R. Pettit: Biosynthetic Products for Cancer Chemotherapy: Volume 3

By George R. Pettit

ISBN-10: 146843408X

ISBN-13: 9781468434088

ISBN-10: 1468434101

ISBN-13: 9781468434101

Fortunately the medical and scientific literature with regards to melanoma chemo­ remedy is now increasing speedily. whereas this is often best for destiny melanoma remedy customers, it truly is changing into more challenging for the entire resear­ chers in chemotherapy-bio-organic chemists concerned with the invention of recent anticancer medicinal drugs, biologists and pharmacologists constructing those new medicines, and physicians doing the scientific research-to preserve abreast of present achievements in those disciplines so extremely important to powerful melanoma remedy. the aim of Volumes 1 and a couple of of this paintings was once to supply beneficial reports of present development in discovery and scientific applica­ tion of latest biosynthetic melanoma chemotherapeutic medicinal drugs. quantity 1 gave a common view of the melanoma challenge and melanoma remedy utilizing biosynthetic items, in accordance with literature to be had via December 1975. quantity 2 integrated quite often the 1st precis of plant and animal biosynthetic antineoplastic and/or cytotoxic parts to April 1976. The survey comprising this 3rd quantity has been divided into sections. part A offers an extension of the quantity 2 info on plant and animal antineoplastic and/or cytotoxic materials to July 1977. The advent to part A brings the precis of such biosynthetic items to literature on hand November 1, 1977. part B includes a precis of information of basically all formerly remoted and characterised marine animal ingredients without reference to organic activity.

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Extra resources for Biosynthetic Products for Cancer Chemotherapy: Volume 3

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528 MELTING POINT: -269 216°C " Me SPECTRAL DATA: UV, IR, PMR, Mass Spec ORGANISM: Chaetomium globosum (Unknown) REFERENCE: 372 [a]o: SOLVENT: OH Chaetoglobosin E MOL. : 530 MELTING POINT: + 158 279-280°C Me SPECTRAL DATA: UV, IR, PMR, Mass Spec ORGANISM: Chaetomium globosum (Unknown) REFERENCE: 372 [a]o: Chaetoglobosin F MOL. n. (Streptomycetaceae) REFERENCE: 173,440 MOL. : 39 OH 787 SPECTRAL DATA: UV, PMR ORGANISM: Streptomyces nogalater REFERENCE: var. n. (Streptomycetaceae) 441 Unknown polysaccharide BIOACTIVITY: ORGANISM: REFERENCE: Ehrlich ascites carcinoma 16 of 20 mice had complete regression at 60 days and 20 mg/kg Culture filtrate Fomes Jomentarius (Polyporaceae) 203 Sporamycin ORGANISM: REFERENCE: Streptosporangium pseudovulgare (No.

1 JLg/ml BIOACTIVITY: 263 REFERENCE: OCH, MOL. : 576 HeLa-S3: EO so , 2 JLg/ml EAC: 30 S-180: 25 LO so , 115 263 BIOACTIVITY: REFERENCE: OCH, CH,-N MOL. : 592 BIOACTIVITY: HeLa: REFERENCE: 263 H E0 50, > 30 JLg/ml Hypoepistephanine MOL. : 594 BIOACTIVITY: REFERENCE: CH,O ~ Cepharanoline EAC: Inactive HeLa: E0 50 , 12 JLg/ml 263 : I ) ~ I ::::".. 0 0 H 29 Higher Plant Alkaloids, Amides, and Ansa Macrolides Stebisimine C 3Ji3SN 20 6 MOL. gfml 263 BIOACTIVITY: REFERENCE: Cepharanthine MOL. gfml 263 BIOACTIVITY: REFERENCE: MOL.

240 HO Oil; Acetate 13S-137°C SPECTRAL DATA: UV, IR, PMR, Mass Spec ORGANISM: Navanax inermis (Cooper) (Mollusca) REFERENCE: 392 MELTING POINT: 61 Chapter 9 62 Hexadecanol MOL. : CH,(CHJ ••CH,OH 242 49°C; 3,5-Dinitrobenzoate, noc Condylac/is gigantea (Coelenterata) 39 MELTING POINT: ORGANISM: REFERENCE: Octadecanol MOL. 5°C Condylactis gigantea (Coelenterata) 39 MELTING POINT: ORGANISM: REFERENCE: Renierin-l C22H33BrO Br 394 MOL. : Oil UV, IR, PMR, Mass Spec Renierafulva (Porifera) 83 MELTING POINT: SPECTRAL DATA: ORGANISM: REFERENCE: I>ebroEnorenierin-l MOL.

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Biosynthetic Products for Cancer Chemotherapy: Volume 3 by George R. Pettit

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